AP Exclusive: Bay Area scientists try 1st gene editing in the body


By Marilynn Marchione | Associated Press

OAKLAND — Scientists for the first time have tried editing a gene inside the body in a bold attempt to permanently change a person’s DNA to try to cure a disease.

Related Articles

Senate GOP will add Obamacare mandate repeal to tax bill

Under new rules, half of US adults have high blood pressure

Analysis: Trump’s pick to cut drug prices oversaw increases

Palo Alto entrepreneur brings tech savvy to an illness that hits home: ALD

Can your heart handle sex?

The experiment was done Monday in Oakland on 44-year-old Brian Madeux. Through an IV, he received billions of copies of a corrective gene and a genetic tool to cut his DNA in a precise spot.

“It’s kind of humbling” to be the first to test this, said Madeux, who has a metabolic disease called Hunter syndrome. “I’m willing to take that risk. Hopefully it will help me and other people.”

Signs of whether it’s working may come in a month; tests will show for sure in three months.

If it’s successful, it could give a major boost to the fledgling field of gene therapy . Scientists have edited people’s genes before, altering cells in the lab that are then returned to patients. There also are gene therapies that don’t involve editing DNA.

But these methods can only be used for a few types of diseases. Some give results that may not last. Some others supply a new gene like a spare part, but can’t control where it inserts in the DNA, possibly …read more

Source:: The Mercury News

(Visited 3 times, 1 visits today)

Leave a Reply

Your email address will not be published. Required fields are marked *